This article originally appeared on Clinical Advisor.

For adolescent men who have sex with men (MSM) participating in a 48-week HIV pre-exposure prophylaxis (PrEP) intervention, adherence decreases with quarterly visits, according to a study published online in JAMA Pediatrics.

Sybil G. Hosek, PhD, from Stronger Hospital of Cook County in Chicago, and colleagues examined the safety of and adherence to PrEP and changes in sexual risk behavior among adolescent MSM. Participants were recruited from adolescent medicine clinics and their community partners; they completed an individualized evidence-based behavioral intervention and were provided with daily tenofovir disoproxil fumarate/emtricitabine for 48 weeks. Seventy-eight adolescents (mean age, 16.5 years) were enrolled (two Asian/Pacific Islanders, 23 blacks/African-Americans, 11 whites, 16 white Hispanics, and 26 participants of other/mixed race/ethnicity).

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